Wine & Cheese parties

These are a no-no for persons who take MAO inhibitors like selegeline against depression. Reason: Tyramine can be taken up into adrenergic nerve terminals or varicosities and then replace norepinephrine. The outpour of norepinephrine then precipitates a hypertensive crisis and accelerates the heart beat. The outcome can be death from stroke or maybe arrhythmia and cardiac arrest. Wine and cheese are foods that contain significant amounts of tyramine - this normally is rapidly metaboized by MAOs and remains inconsquential, except when the enzymes are inhibited.