I am sorry we did not have time to cover that. But you should be aware of the various drugs useful in treating, symtomatically by reducing intraocular pressure, close angle glaucoma. In the end it is quite easy, though initially looking complex: You have to just remember the anatomy of the anterior eye structures and where the receptors are located.
- Circular muscle has M receptors.
- Radial muscle has alpha1 receptors.
- Cilial muscle has M-receptors.
- Cilial epithelium has beta-2 receptors (and these control aqueous humor production).
- Alpha-2 receptors are located - where? No idea. but stimulating them with agonist opens alternative uveoscleral fluid outflow.
Contracting the iris re-establishes some Canal of Schlemm outflow. All of this ism like an autonomic clearing house!
Additionally to using ANS drugs, one can reduce aqueous humor outflow by using (a) a carbonic anhydrase inhibitor, like aceazolamide, or (b) one can draw fluid from the eye osmotically by increasing plasma osmolality with glycerol (just by drinking a cup of it) or injected mannitol.
In reality, 2-3 of these approaches are employed!
Additionally to using ANS drugs, one can reduce aqueous humor outflow by using (a) a carbonic anhydrase inhibitor, like aceazolamide, or (b) one can draw fluid from the eye osmotically by increasing plasma osmolality with glycerol (just by drinking a cup of it) or injected mannitol.
In reality, 2-3 of these approaches are employed!
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